RNA Details
Disease Name
idiopathic pulmonary fibrosis
Tissue
lung
RNA Symbol
let-7d-5p
RNA ID
RNA Type
miRNA
Alteration Pattern
dysregulation
Species
homo sapiens
Detection Methods
ROC analysis; qRT-PCR; Signaling pathways prediction etc.
Target
NA
Pathway
NA
PubMed ID
Title
Plasma microRNAs are associated with acute exacerbation in idiopathic pulmonary fibrosis
Year
2016
Function
"Let-7d-5p was decreased in S-IPF and further decreased in AE-IPF, when compared to NC. While miR-25-3p was obviously decreased in S-IPF but significantly increased in AE-IPF. MiR-25-3p and let-7d-5p in plasma were differentially expressed between AE-IPF and S-IPF. A combination of these two miRNAs may be a potential biomarker for AE-IPF from IPF. Acute exacerbation of idiopathic pulmonary fibrosis (AE-IPF), Stable-IPF (S-IPF)."